Fig. 5

Spearman’s rank correlation analysis between dry eye indices and gut microbiome at the phylum level. a NEI score showed significant positive relation with Cyanobacteria (r = 0.584, p = 0.003). b Tear secretion was negatively related with Proteobacteria (r = − 0.421, p = 0.015). c Tear secretion with body weight adjustment showed negative relation with Cyanobacteria (r = − 0.494, p = 0.004). NEI: National Eye Institute