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Table 1 Dissociation constants (μM) of GroEL binding to host molecules

From: GroEL protein of the Leptospira spp. interacts with host proteins and induces cytokines secretion on macrophages

 

GroEL

LigBC

(positive control)

Lp25

(negative control)

Collagen I

0.011 ± 0.004

0.008 ± 0.002

0.699 ± 0.587

Collagen IV

0.006 ± 0.001

0.007 ± 0.001

2.420 ± 0.001

Laminin

0.115 ± 0.012

0.041 ± 0.003

1.136 ± 0.959

Plasminogen

0.031 ± 0.002

0.005 ± 0.001

4.433 ± 0.074

Plasma

0.034 ± 0.003

0.015 ± 0.002

5.368 ± 0.959

Fibronectin

0.010 ± 0.001

0.006 ± 0.001

6.3690 ± 3.608

Fibrinogen

0.023 ± 0.003

0.004 ± 0.001

0.606 ± 8.044

Elastin

0.023 ± 0.003

0.004 ± 0.001

0.606 ± 8.044

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BMC Microbiology

ISSN: 1471-2180

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