Fig. 1From: GroEL protein of the Leptospira spp. interacts with host proteins and induces cytokines secretion on macrophagesa Schematic representation of GroEL from L. interrogans. Three structural domains are presented: apical (AD), intermediate (ID) with two subdomains (I1 and I2), and equatorial (ED) consisting of subdomains E1 and E2. In detail are shown three highly conserved GroEL regions: residues 191–202 (GMQFDRGYISPY); residues 362–381 (EKLQERLAKLAGGVAVIHVG), and residues 401–415 (ATRAAVEEGIVPGGG. b The predicted 3D structural model of L. interrogans GroEL generated using the SWISS-MODEL protein homology modeling serverBack to article page