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Fig. 2 | BMC Microbiology

Fig. 2

From: Azithromycin and the microbiota of cystic fibrosis sputum

Fig. 2

CF microbial community comparison between Responders and Non-Responder to azithromycin treatment. Alpha diversity (within patients) of Responders and Non-Responders based on Shannon diversity index (SDI) metrics for the whole cohort (n = 38 patients) and the naïve cohort (n = 29) when only the Pre (i.e. Pre and Day 0) (a) or baseline samples (b) were analyzed. Wilcoxon rank sum test was performed. NMDS plot showing beta diversity of R and Non-R based on Bray-Curtis dissimilarities when only the Pre (i.e. Pre and Day 0) (c) or baseline samples were analysed (d). ASVs that were identified by DESeq2 to be significantly different (p adjusted < 0.05) between Responders and Non-Responders, when Pre (i.e. Pre and Day 0) (e) or baseline samples were analysed (f), relative abundance is presented in the Log2 scale. Boxplots show the median with IQR and the ends of the whiskers mark the 10th and the 90th percentiles. R: responder and Non-responders (NR) to the azithromycin treatment, ASV: amplicon sequence variants

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