Effects of Clostridium butyricum on growth performance, metabonomics and intestinal microbial differences of weaned piglets

Table 4 Different endogenous metabolites in the feces of weaned piglets after adding C. butyricum

Super class	Metabolite names	Precurso type	m/z^a	Rt^b	log2fc_CB/NC^c	P-value	Trend^d
Amino acids	Citrulline	[M-H]-	174.09	101.75	1.71	< 0.001	↑
Amino acids	Acetyl-DL-Valine	[M-H]-	158.08	306.14	0.83	0.009	↑
Amino acids	L-citrulline	[M + H]+	176.10	102.20	1.05	0.027	↑
Amino acids	L-valine	[M-H]-	115.92	1010.69	−0.60	0.034	↓
Amino acids	4-hydroxy-L-proline	[M-H]-	129.98	207.29	0.80	0.044	↑
Drugs	Cimaterol	[M + H]+	220.15	565.94	0.95	0.012	↑
Amine	N-acetylhistamine	[M-H]-	152.08	778.56	−2.04	0.011	↓
Lipids	Phosphatidylinositol lyso 16:0	[M-H]-	571.29	738.01	−3.50	0.001	↓
Lipids	Sebacic acid	[M-H]-	201.11	561.47	1.42	0.001	↑
Lipids	Suberic acid	[M-H]-	173.08	452.26	1.19	0.011	↑
Lipids	Azelaic acid	[M-H]-	187.10	508.95	1.38	0.019	↑
Lipids	Dodecanedioic acid	[M-H]-	229.14	657.55	0.72	0.024	↑
Lipids	Phosphatidylethanolamine lyso 18:2	[M-H]-	476.28	827.81	−1.06	0.028	↓
Organic acids	O-toluic acid	[M-H]-	135.05	538.95	1.11	0.002	↑
Organic acids	3-methylglutaric acid	[M-H]-	145.05	380.25	1.53	0.003	↑
Organic acids	Indole-3-carboxylic acid	[M-H]-	160.04	504.67	1.38	0.014	↑
Organic acids	4-acetamidobutanoic acid	[M-H]-	144.07	264.59	1.23	0.015	↑
Organic acids	Nonic Acid	[M + H]+	189.11	513.04	1.72	0.016	↑
Organic acids	Trans-3-coumaric acid	[M-H]-	163.04	459.07	−1.48	0.023	↓
Organic acids	Xanthurenic acid	[M-H]-	204.03	464.26	−1.39	0.028	↓
Organic acids	2,3-dihydroxybenzoic acid	[M-H]-	153.02	397.38	−1.22	0.037	↓
Organic acids	2-phenylpropionic acid	[M-H]-	149.06	601.41	0.88	0.041	↑

^am/z, mass-to-charge ratio; ^bRT, retention time; ^cFC fold change; ^d″↑/↓” indicate the increase/decrease in the metabolite level after adding C. butyricum to the diet (n = 6)

ISSN: 1471-2180