Fig. 6

Comparisons of genus (or higher-level OTU classifications in the absence of genus-level taxonomic information) in bronchial washing and PSB samples from the NTM-PD and control groups. a Bronchial washing samples. b PSB samples. The volcano plots show the relative fold changes and whether they were significant. Differences were assessed using Student’s t-test; the p-values for each genus (or higher-level OTU in the absence of genus-level taxonomic data) represent the statistical significance of abundance changes in the NTM-PD group compared with the control group. Red indicates statistical significance (p < 0.05) after adjustment for BMI (by ANCOVA). NTM-PD, non-tuberculous mycobacterial pulmonary disease; PSB, protected specimen brushing; BMI, body mass index