Fig. 1

Eukaryotic microbial community composition across sample sites. Differences in the eukaryotic microbial community composition on skin (a) and in anterior nares (b) between AD patients and non-AD healthy controls were examined using Jaccard distances and here visualized using principal coordinates analysis (PCoA). The analysis of similarity test (ANOSIM) was used for pairwise comparison between the following sample sites: i) AD LS and NLS (R = 0.00, p = 0.48), ii) AD LS and control skin (R = 0.12, p = 0.0001, adjusted p = 0.0012), iii) AD NLS and control skin (R = 0.10, p = 0.0001, adjusted p = 0.0012) and iv) AD nose and control nose (R = 0.06, p = 0.003, adjusted p = 0.03). P-values were adjusted for mass significance using the Bonferroni method. Abbreviations: AD: atopic dermatitis, LS: lesional skin, NLS: non-lesional skin