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Fig. 3 | BMC Microbiology

Fig. 3

From: Phenomic profiling of a novel sibling species within the Scedosporium complex in Thailand

Fig. 3

TMMI-012 induces monocyte death in vitro and shortens lifespan in vivo. a Acridine orange-ethidium bromide (AO/EB) staining of human monocyte cell line (THP-1) after being infected with S. boydii, C. albicans, A. fumigatus, or TMMI-012. b Percentage of cell death by apoptosis of THP-1 cells after being infected with S. boydii, C. albicans, A. fumigatus, or TMMI-012. The results are based on the analysis of apoptosis cells following AO/EB staining (n = 5). c Survival percentages during post-inoculation periods of mice infected with S. boydii, L. prolificans, TMMI-012, or uninfected controls (n = 3). d Survival percentages during post-inoculation periods of G. mellonella infected with S. boydii, L. prolificans, TMMI-012, or uninfected controls. Data shown as mean ± SD; P-value calculated by one-way ANOVA with Tukey’s post hoc test; *P < 0.05. For survival analysis, lifespan is analyzed using Kaplan-Meier analysis

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