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Table 4 Prophage sequences present in sequenced clostridial genomes. Pvalue – p-value in Fisher’s exact test, padjust – p-value, adjusted for multiple hypothesis testing, odds ratio – odds of recurrent infection, %single/recurrent – percentage of sequences with prophage present in single/recurrent infections. Adjusted p-values < 0.05 were considered significant

From: Higher genome variability within metabolism genes associates with recurrent Clostridium difficile infection

 

pvalue

padjust

odds ratio

%single

%recurrent

Prophage_134287341 NC_009231 putative scaffold protein {Clostridium phage phiC2}

4.85E-03

1.60E-01

0.11

17%

2%

Prophage_90592671 NC_007917 putative lysin {Clostridium phage phi CD119}

6.91E-03

1.60E-01

0.26

31%

10%

Prophage_90592670 NC_007917 putative holin {Clostridium phage phi CD119}

1.50E-02

1.60E-01

0.32

81%

57%

Prophage_80159693 NC_007581 putative IS transposase (OrfA) {Clostridium phage c-st}

1.64E-02

1.60E-01

0.23

19%

5%

Prophage_90592681 NC_007917 repR RepR putative repressor {Clostridium phage phi CD119}

1.64E-02

1.60E-01

0.23

19%

5%

Prophage_90592642 NC_007917 putative head protein {Clostridium phage phi CD119}

1.84E-02

1.60E-01

0.08

11%

1%

Prophage_134287355 NC_009231 putative tail tape measure protein {Clostridium phage phiC2}

3.02E-02

2.07E-01

0.33

28%

11%

Prophage_134287357 NC_009231 putative hydrolase {Clostridium phage phiC2}

3.24E-02

2.07E-01

0.20

14%

3%

Prophage_134287371 NC_009231 putative amidase/endolysin {Clostridium phage phiC2}

3.60E-02

2.07E-01

0.31

22%

8%

Prophage_134287356 NC_009231 putative LysM {Clostridium phage phiC2}

4.20E-02

2.07E-01

0.27

19%

6%

Prophage_90592656 NC_007917 xkdP XkdP protein {Clostridium phage phi CD119}

4.37E-02

2.07E-01

0.40

78%

58%