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Table 1 Functional categories of 108 genes whose deletion mutants are sensitive to 0.03% SDS

From: Genome-wide identification for genes involved in sodium dodecyl sulfate toxicity in Saccharomyces cerevisiae

Function

Genes

Metabolism (16)

PRS3*

THR4**

ARG82****

REG1***

IPK1***

ARO1*****

TRP1*****

TRP5*****

ELM1*****

AYT1*

ELO3*****

ARO7*****

ARO2****

NRK1****

GRR1****

ERG3****

Cell cycle and DNA processing (14)

NEM1****

CDC50*****

SLX5***

PHO85***

MSH1***

DCC1***

EAF1**

XRS2

RSC2***

FYV6****

ARP5**

CTF4**

RSC1*

SLX8*

  

Transcription (14)

BRE1**

BDF1*****

DEP1*

SAC3****

MOT2*****

DEG1***

SFL1*

POP2****

CTK1***

LSM1*

SRB5***

SPT4*

IKI3***

SGF29*

  

Cellular transport, transport facilities and transport routes (28)

GOS1****

PHO87**

VPS23*****

VMA3*****

YPT31****

LOA1***

VMA13****

VPS22*****

VPS36*****

VPS38****

VPS37*****

VPS63*****

VPS24****

VPS25*****

RCY1*****

VPS51****

CHS5*****

VPS32*****

ISA1****

PIL1**

VMA5****

VPS20*****

VPS16*****

VPS1*****

VPS33*****

VPS64**

VMA21*****

VID22****

    

Protein with binding function or cofactor requirement (structural or catalytic) (9)

DIA4****

RPL35A**

NUP84**

APL2****

MAP 1**

RPL13B**

CBP3**

HIT1*

OCT1**

       

Biogenesis of cellular components (5)

MDM10***

MRPL32*

MRPL24**

GIM5*

MDM20*****

   

Cell wall integrity and osmotic stress response (7)

TUS1***

ROM2***

SIT4***

TOH1*****

SLG1*

LAS21**

PBS2****

 

Unclassified proteins (15)

SRF1*

YDL041W*

YLR358C**

YNL296W***

YPR123C***

YDR149C*

YOR331C*****

YGR272C*

YLR374C*

YKL136W*

YGR160W*

BRP1****

BUD30*

API2**

YDR008C*

 
  1. The number of asterisks represents SDS-sensitivity of different mutants. Mutant with five asterisks was most sensitive to SDS stress, while mutant with one asterisk was least sensitive to SDS