Skip to main content
Fig. 5 | BMC Microbiology

Fig. 5

From: Epidemic ribotypes of Clostridium (now Clostridioides) difficile are likely to be more virulent than non-epidemic ribotypes in animal models

Fig. 5

Fecal-associated Toxin A and B was significantly higher in hamsters infected with epidemic ribotype of C. difficile in the hamster CDI model. For each isolate, hamsters were split into groups of 5, housed individually, and orally inoculated with a specific titer of spores. Fecal pellets were collected every 24 h, then weighed and processed for detection of Toxin A and B by an ELISA. Toxin levels were normalized to the numbers of CFU recovered. a Toxin A and b Toxin B levels were higher in hamsters infected with epidemic isolates. These data represent the average of 5 independent data points, and error bars indicated the standard error of the means. Asterisks denote significant differences between toxin values at p < 0.05 (Two-way ANOVA with Tukey’s post-hoc test; p < 0.05)

Back to article page