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Table 7 Variations in transcription factors before and after nucleotide changes (− 338, − 155 and − 31) in the IL1B gene by using AliBaba2.1 software

From: First insights into the molecular basis association between promoter polymorphisms of the IL1B gene and Helicobacter pylori infection in the Sudanese population: computational approach

SNP Site

Base Group

TF

TFBSs Sequence

TF Position

−338

A

GCR1

CTTCCACTTT

− 343 _ -334

 

GR

CACTTTGTCC

− 339 _ -330

T

PU.1

CTTCCTCTTT

− 343 _ -334

 

GCR1

  

−155

G

Zen-1

ATTATCTCAG

−164 _ -155

 

GATA-1

TTATCTCAG

− 163 _ -154

C

C/EBPbeta

ATTATCTCAC

−164 _ -155

 

Zen-1

  
 

GATA-1

TTATCTCACT

−163 _ -154

−31

C

–

–

–

T

RSRFC4

GCTATAAAAA

−33 _ -24