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Table 6 Allele and genotype frequencies of IL1B-31 polymorphism among H. pylori infected and uninfected subjects, and their contributions to H. pylori infection

From: First insights into the molecular basis association between promoter polymorphisms of the IL1B gene and Helicobacter pylori infection in the Sudanese population: computational approach

  H. pylori (+ve)
n = 61
H. pylori (−ve)
n = 61
OR (95% CI)*
Allele frequency
IL1B-31-C 77 (63.11%) 93 (76.23%) 0.5336 (0.3060–0.9304)
IL1B-31-T 45 (36.89%) 29 (23.77%)
 P-value 0.0363  
Genotype frequency
 C/C 28 (45.90%) 40 (65.57%) 1 (reference)
 T/C 21 (34.41%) 13 (21.31%) 0.4333 (0.1864–1.008)
 T/T 12 (19.67%) 8 (13.12%) 0.4667 (0.1688–1.290)
 T/C + T/T 33 (54.1%) 21 (34.43%) 0.4455 (0.2147–0.9243)
 P-value 0.0445  
  1. *OR, odds ratio; 95%CI, 95% confidence interval