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Table 3 Summary of the in silico predicted TFBSs for the [−368_ + 10] region

From: First insights into the molecular basis association between promoter polymorphisms of the IL1B gene and Helicobacter pylori infection in the Sudanese population: computational approach

Transcription factor Positiona SNP in binding site Software
Start End AliBaba2.1 Alggen Promo Tfsitescan TF-Binding GPMiner
GR − 345 − 327 rs140623868
NG_008851.1:g.4666 A > Tb
X X X X  
NF-kappaB −297 − 288   X X X X  
c-Myb − 269 − 260 rs769027934   X X X  
Oct-1 − 233 − 225   X   X X  
GATA-1 − 227 − 214 rs749558279 X X X X X
GR − 207 − 202    X X X  
GATA-1 −164 −155 rs866837107
NG_008851.1:g.4844 G > Cb
X X X   
Sp1 − 149 − 132 rs74579367 X   X   
AP-2 − 148 − 137    X X  
MAZ − 147 −137   X X   X
NF-Y − 126 −114    X X X  
NF-AT − 116 − 105    X    X
Spi-1/PU.1 −115 −97   X   X   
STAT1 − 108 − 101    X   X X
IRF − 106 −99    X X   
C/EBPalpha −94 −83    X   X X
NF-kappaB −70 − 61 rs4986962 X    X  
HSTF/HSF −69 −60 X    X  
C/EBP −67 −58 X    X  
Spi-1/PU.1 −50 −39   X   X   
TBP −31 −25 rs1143627b   X   X X
c-Myb −14 −5    X   X X
NF-1 −13 −4   X X   X  
GATA-1 −7 6 rs529869449   X X X X
  1. aPositions are given relative to the translational IL1B start codon (transcript NM_000576.3)
  2. bSNPs observed in this study