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Table 5 Organ weights of male and female (mice) treated orally with P. acidilactici J9 for 14 days

From: Two-weeks repeated-dose oral toxicity study of Pediococcus acidilactici J9 in a mice model

   (Unit: g)
Sex Organs Dose (mg)
Control 500 1000 2000
Male Brain 0.445 ± 0.014 0.440 ± 0.014 0.444 ± 0.015 0.437 ± 0.016
Lung 0.124 ± 0.013 0.126 ± 0.006 0.125 ± 0.010 0.134 ± 0.023
Liver 0.984 ± 0.208 0.920 ± 0.065 0.929 ± 0.183 0.904 ± 0.176
Heart 0.104 ± 0.011 0.101 ± 0.007 0.100 ± 0.008 0.105 ± 0.010
Kidney(L) 0.129 ± 0.025 0.128 ± 0.025 0.127 ± 0.13 0.126 ± 0.018
Kidney(R) 0.133 ± 0.025 0.136 ± 0.011 0.134 ± 0.017 0.140 ± 0.029
Testis(L) 0.071 ± 0.020 0.067 ± 0.000 0.067 ± 0.008 0.071 ± 0.006
Testis(R) 0.074 ± 0.024 0.070 ± 0.000 0.063 ± 0.018 0.074 ± 0.007
Spleen 0.057 ± 0.009 0.052 ± 0.007 0.050 ± 0.006 0.054 ± 0.014
Thymus 0.042 ± 0.010 0.046 ± 0.007 0.044 ± 0.007 0.045 ± 0.008
Female Brain 0.443 ± 0.014 0.434 ± 0.019 0.437 ± 0.013 0.431 ± 0.018
Lung 0.120 ± 0.006 0.120 ± 0.008 0.134 ± 0.014 0.121 ± 0.017
Liver 0.775 ± 0.065 0.788 ± 0.199 0.755 ± 0.092 0.727 ± 0.103
Heart 0.091 ± 0.007 0.089 ± 0.005 0.105 ± 0.007 0.084 ± 0.007
Kidney(L) 0.114 ± 0.025 0.102 ± 0.011 0.126 ± 0.007 0.102 ± 0.010
Kidney(R) 0.110 ± 0.011 0.110 ± 0.013 0.140 ± 0.012 0.105 ± 0.012
Ovary (L) 0.001 ± 0.000 0.002 ± 0.000 0.002 ± 0.000 0.001 ± 0.000
Ovary(R) 0.002 ± 0.000 0.002 ± 0.000 0.002 ± 0.000 0.002 ± 0.000
Spleen 0.058 ± 0.007 0.052 ± 0.010 0.053 ± 0.010 0.051 ± 0.007
Thymus 0.077 ± 0.007 0.071 ± 0.010 0.045 ± 0.011 0.076 ± 0.014
  1. Values are expressed as mean ± SE (n = 5)
  2. NS not significantly different among groups
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BMC Microbiology

ISSN: 1471-2180

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