Table 4 Gross findings of male and female (mice) treated orally with P. acidilactici J9 for 14 days
From: Two-weeks repeated-dose oral toxicity study of Pediococcus acidilactici J9 in a mice model
Sex | Male | Female | |||||||
|---|---|---|---|---|---|---|---|---|---|
Dose (mg) | Control | 500 | 1000 | 2000 | Control | 500 | 1000 | 2000 | |
Brain | NGF | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |
Lung | NGF | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |
Liver | NGF | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |
Heart | NGF | 4(90) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |
Kidney(L) | NGF | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |
Kidney(R) | NGF | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |
Testis(L) | NGF | 5(100) | 5(100) | 5(100) | 5(100) | Â | Â | Â | Â |
Testis(R) | NGF | 5(100) | 5(100) | 4(90) | 5(100) | Â | Â | Â | Â |
Ovary(L) | NGF | Â | Â | Â | Â | 5(100) | 5(100) | 5(100) | 5(100) |
Ovary(R) | NGF | Â | Â | Â | Â | 5(100) | 5(100) | 5(100) | 5(100) |
Spleen | NGF | 4(90) | 4(90) | 5(100) | 5(100) | 3(70) | 4(90) | 5(100) | 5(100) |
Thymus | NGF | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) | 5(100) |