TY - JOUR AU - Erum, Rakhshanda AU - Samad, Farkhunda AU - Khan, Adnan AU - Kazmi, Shahana Urooj PY - 2020 DA - 2020/12/03 TI - A comparative study on production of extracellular hydrolytic enzymes of Candida species isolated from patients with surgical site infection and from healthy individuals and their co-relation with antifungal drug resistance JO - BMC Microbiology SP - 368 VL - 20 IS - 1 AB - Surgical site infection (SSI) is a crucial dilemma of surgery. Patients with SSIs not only face difficulty in treatment but also bear extra cost with high mortality rate. Resistant strains of Candida have emerged as an important nosocomial pathogen. Proteinase and phospholipase are exo- enzymes of Candida species, have importance with respect to their contribution in diseases. This study focused on prevalence of Candida species in surgical wound, their resistance to antifungal drugs, co-relation of these resistance with virulence potential of Candida species and comparison of production level of exo-enzymes of Candida species isolated from patients with SSIs and healthy individuals to highlights their role in SSIs. SN - 1471-2180 UR - https://doi.org/10.1186/s12866-020-02045-6 DO - 10.1186/s12866-020-02045-6 ID - Erum2020 ER -