Fig. 4

Principal coordinates analysis (PCoA) plot of pubertal and non-pubertal subjects (a), younger children and pre-pubertal subjects (b), early-, middle-, late-pubertal subjects (c), pre-pubertal and early-pubertal subjects (d), and younger children and late-pubertal subjects (e). The plots show the first two principal coordinates (axes) for PCoA using Bray-Curtis Distance method, and Statistical method PERMANOVA