Fig. 7
From: Berberine alters gut microbial function through modulation of bile acids
Clostridium hiranonis expresses a gene cluster encoding a xenobiotic response transcription factor during berberine treatment. a. Heat map of differentially expressed genes (log2FC > (−)0.58; P < 0.05) by C. hiranonis in the mouse cecum between control diet and berberine treatment. b. Organization and gene fold change of a gene cluster highly upregulated by berberine. c. Network displaying interactions between expressed genes and bile acid metabolome in control mice. d. Network displaying interactions between expressed genes and bile acid metabolome in berberine-treated mice. Data points with Spearman’s correlations < 0.7 and a P values < 0.05 are displayed