Fig. 3
From: Berberine alters gut microbial function through modulation of bile acids
Effect of berberine on Bilophila wadsworthia on in vivo gene expression and network interactions. a. Heat map of differential gene expression (log2FC > (−)0.58; P < 0.05) for B. wadsworthia grouped by function. b. Network interactions between B. wadsworthia cecal gene expression and bile acid profile from cecum, liver, and serum in control group. c. Network interactions between B. wadsworthia cecal gene expression and bile acid profile from cecum, liver, and serum in berberine-treated group. d. Sub-network showing interactions between DCA in the cecum and gene expression as well as gene expression interaction with nitrate reductase. Data points with Spearman correlations < 0.7 and a P values < 0.05 are displayed