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Table 5 Marker taxa analysis. Comparisons between the South African (RSA) cohorts data and benchmarked data sets from the curatedMetagenomicData (cMD). (a) cMD Western (W) data vs RSA data and (b) cMD non-Western (NW) data vs RSA data. The Kruskal-Wallis (KW) rank sum test was used in the calculation of the p-values

From: Gut microbiome profiling of a rural and urban South African cohort reveals biomarkers of a population in lifestyle transition

A

Genus

RSA Median

W-Median

W-log2FC

p-values (KW)

Prevotella

0.543

0.030

4.409

2.20E-16

Treponema

0.116

0.003

5.085

6.30E-01

Bifidobacterium

0.015

0.043

-4.139

3.09E-16

Barnesiella

0.049

0.033

-0.552

1.39E-01

Akkermansia

0.056

0.012

0.251

9.39E-01

Alistipes

0.040

0.118

-2.789

2.20E-16

Bacteroides

0.268

0.384

-1.183

1.08E-08

Parabacteroides

0.043

0.050

-0.719

7.21E-05

B

Genus

RSA Median

NW-Median

NW-log2FC

p-values (KW)

Prevotella

0.543

0.760

-4.685

1.02E-03

Treponema

0.116

0.001

1.638

5.18E-01

Bifidobacterium

0.015

0.097

-1.159

2.20E-16

Barnesiella

0.049

0.001

4.481

6.28E-14

Akkermansia

0.056

0.001

3.227

9.20E-03

Alistipes

0.040

0.008

3.917

3.59E-03

Bacteroides

0.268

0.020

4.243

2.20E-16

Parabacteroides

0.043

0.006

3.091

2.20E-16