Gut microbiome profiling of a rural and urban South African cohort reveals biomarkers of a population in lifestyle transition

Table 3 Alpha and beta diversity significance of compared groups. Alpha diversity p-values were calculated with pairwise Wilcoxon rank sum test. Bray-Curtis diversity p-values were calculated with PERMANOVA

Sample Distribution	Group Comparisons	Shannon p-values	Chao1 p-values	Bray-Curtis p-values
Bushbuckridge and Soweto	Lean vs Obese	0.72	0.06	0.07
Bushbuckridge and Soweto	Lean vs Lean	0.69	0.72	0.01
Bushbuckridge and Soweto	Obese vs Obese	0.01	< 0.001	0.001
All samples	Bushbuckridge vs Soweto	0.01	< 0.001	0.001
Bushbuckridge	Lean vs Obese	0.85	0.001	0.02
Soweto	Lean vs Obese	0.45	0.33	0.84

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