Table 1 Analysis of transcriptional level of selected genes coding for proteins up and down-regulated in S. lugdunensis cultivated in BHI with DIP versus grown in BHI
Protein | Gene | Proteomic fold-changea | Transcriptomic fold-change | Transcriptomic p-value |
|---|---|---|---|---|
Iron-regulated Surface Determinant J | isdJ | 8.74 | 183.64 | 7.50e-04 |
Iron-regulated Surface Determinant B | isdB | 8.18 | 240.73 | 3.19e-05 |
Iron-siderophore ABC transporter | sirA | 7.31 | 21.24 | 3.40e-03 |
Transferin-binding protein | SLUG_14730 | 7.08 | 45.84 | 1.78e-05 |
Siderophore ABC transporter | sstD | 7.06 | 95.74 | 4.02e-05 |
Catalase | katA | -3.83 | -6.35 | 6e-04 |
Nitrate reductase subunit alpha | narG | -4.65 | -1.96 | 3.81e-02 |
Formate dehydrogenase subunit alpha | SLUG_07190 | -5.04 | -2.23 | 7.24e-03 |
NAD(P)/FAD-dependent oxidoreductase | nasD | -6.04 | -2.21 | 1.12e-02 |