Kaplan-Meier survival curves of larvae of G. mellonella after infection with around 1 × 107
CFU of S. lugdunensis previously cultivated in BHI (dark blue line), in BHI supplemented with 350 μM DIP (light blue line), in BHI with 350 μM DIP and 2 mM FeSO4 (black), and sterile saline buffer without cells (grey line). *: p = 1 × 10− 5. **: p = 3.9 × 10− 6. In this animal model, virulence of S. lugdunensis previously cultivated in presence of DIP was significantly reduced.