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Table 3 Sensitivity and specificity for the mCIM combined with eCIM to detect different types of carbapenemase

From: Combination of modified carbapenem inactivation method (mCIM) and EDTA-CIM (eCIM) for phenotypic detection of carbapenemase-producing Enterobacteriaceae

mCIM + eCIM

blaOXA-48

blaKPC

blaNDM

blaIMP

blaVIM

blaNDM/blaOXA-48d

blaKPC/blaOXA-48

total

TP (n)

–

–

15

6

3

1

–

25

FN (n)

–

–

0

1

0

2

–

3

TN (n)

40c

34

–

–

–

–

2

76

FP (n)

1

0

–

–

–

–

0

1

Sensitivity (%)a

–

–

100

85.7

100

33.3

–

89.3

Specificity (%)b

97.6

100

–

–

–

–

100

98.7

  1. aSensitivity = TP/TP + FN
  2. bSpecificity = TN/TN + FP
  3. cThe results of 2 mCIM tests were interpreted as “indeterminate” (pinpoint colonies were present within a 16- to 18-mm zone)
  4. dIsolates with blaNDM/blaOXA-48 were defined as metallo-carbapenemase positive
  5. TP true positive, FN false negative
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BMC Microbiology

ISSN: 1471-2180

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