From: Lifestyle modifications result in alterations in the gut microbiota in obese children
Fat loss group | Fat gain group | |||
---|---|---|---|---|
pre (n = 17) | post (n = 17) | pre (n = 19) | post (n = 19) | |
Anthropometric measurements | ||||
Weight (kg) | 57.50 ± 16.90 | 57.38 ± 16.72 | 57.60 [49.40; 67.70] | 60.20 [50.00; 68.90]** |
Weight (z-score) | 2.38 ± 0.76 | 2.29 ± 0.77** | 2.16 [1.93; 2.50] | 2.20 [1.94; 2.64] |
Height (cm) | 145.76 ± 14.80 | 146.78 ± 14.59** | 148.73 ± 14.62 | 149.75 ± 14.59** |
Height (z-score) | 0.98 [0.17; 2.16] | 1.04 [0.18; 2.17] | 1.26 [0.75;1.46] | 1.15 [0.86; 1.48] |
BMI (kg/m2) | 26.41 ± 4.04 | 26.01 ± 4.00** | 25.70 [23.75; 27.30] | 26.14 [23.94; 28.13]* |
BMI (z-score) | 2.54 [1.95; 2.76] | 2.36 [1.88; 2.65]** | 2.22 [1.96; 2.54] | 2.34 [2.02; 3.54] |
Systolic blood pressure (mmHg) | 119.71 ± 13.74 | 118.18 ± 9.34 | 121.05 ± 11.71 | 119.26 ± 11.96 |
Diastolic blood pressure (mmHg) | 77.00 [70.00; 82.00] | 76.00 [69.00; 83.00] | 72.05 ± 10.31 | 73.63 ± 10.72 |
Waist circumference (cm) | 88.90 [75.00; 93.20] | 84.50 [74.80; 93.90]** | 88.81 ± 13.26 | 90.07 ± 13.64* |
Waist-to-height ratio | 0.58 [0.54; 0.61] | 0.56 [0.53; 0.60]** | 0. 59 [0.55; 0.62] | 0.59 [0.56; 0.62] |
Total body fat (%) | 38.30 [35.60; 43.0] | 37.2 [34.40; 39.70]** | 38.79 ± 5.16 | 39.34 ± 5.06* |
Skeletal muscle mass (kg) | 17.70 [13.90; 21.80] | 18.20 [14.20; 26.90]** | 17.80 [15.70; 22.70] | 19.40 [16.00; 23.80] |
Total body fat (kg) | 22.80 ± 7.89 | 21.99 ± 7.40** | 21.60 [18.80; 26.80] | 23.20 [19.20; 28.20]** |
Visceral Fat (cm2) | 112.10 [74.30; 144.20] | 105.10 [71.90; 136.80]** | 118.76 ± 49.54 | 123.76 ± 49.10** |
Abdomen fat (%) | 0.85 ± 0.08 | 0.85 ± 0.08 | 0.86 ± 0.10 | 0.87 ± 0.09 |
Blood biochemical profiles | ||||
Glucose (mg/dL) | 98.00 [95.00; 103.00] | 99.00 [98.00; 103.00] | 104.00 [100.0; 106.0] | 99.00 [95.50; 107.00] |
AST (IU/L) | 24.00 [21.00; 29.00] | 24.00 [19.00; 26.00] | 24.000 [20.50; 30.50] | 24.00 [20.00; 28.50] |
ALT (IU/L) | 20.0 [17.00; 35.00] | 18.00 [16.00; 24.00]* | 25.00 [15.00; 46.50] | 26.00 [15.00; 42.50] |
Total cholesterol (mg/dL) | 177.00 ± 30.20 | 176.18 ± 31.84 | 169.58 ± 22.99 | 173.84 ± 18.90 |
Triglyceride (mg/dL) | 90.00 [68.00; 117.00] | 91.00 [67.00; 108.00] | 77.00 [72.00; 115.00] | 86.00 [64.00; 137.50] |
HDL cholesterol (mg/dL) | 50.94 ± 11.17 | 51.18 ± 10.67 | 52.47 ± 10.11 | 53.37 ± 10.87 |
LDL cholesterol (mg/dL) | 108.29 ± 24.00 | 107.06 ± 27.04 | 102.32 ± 22.18 | 104.74 ± 19.33 |
hs-CRP (mg/L) | 1.40 [0.60; 2.60] | 1.40 [0.70; 1.90] | 1.20 [0.80; 1.60] | 1.60 [0.80; 2.00] |
Uric acid (mg/L) | 4.90 [4.40; 5.40] | 4.80 [4.50; 5.50] | 5.51 ± 0.93 | 5.79 ± 0.74 |
25-OH vitamin D (ng/mL) | 16.08 ± 5.81 | 16.92 ± 6.44 | 13.63 ± 4.33 | 16.72 ± 5.92 |
Ferritin (ng/mL) | 64.50 [48.30; 83.70] | 68.70 [51.90; 96.20] | 54.90 [41.40; 139.60] | 59.80 [46.55; 111.75] |
Insulin (μU/mL) | 15.54 [10.75; 27.49] | 11.63 [8.17; 16.12]** | 19.29 [11.90; 39.21] | 13.93 [10.43; 22.91]** |
HbA1c (%) | 5.4 ± 0.3 | 5.4 ± 0.2 | 5.40 [5.35; 5.50] | 5.40 [5.30; 5.50] |
HOMA-IR | 1.33 [1.22; 1.42] | 2.67 [2.05; 3.84]** | 1.39 [1.33; 1.46] | 2.99 [2.60; 6.17]** |