Fig. 4
From: Experimental determination of evolutionary barriers to horizontal gene transfer
Dosage sensitivity. Selection coefficients of newly transferred and deleterious genes from S. Typhimurium (white bars) expressed in E. coli background overlaid with those of their orthologs from E. coli (grey bars) expressed in E. coli background. On the x-axis genes are sorted according to their selection coefficients for the transfer of E. coli orthologs. Genes marked with asterisks show dosage sensitivity, as the fitness cost of the additional copies of an E. coli gene is the same or greater than the fitness cost of its S. Typhimurium ortholog