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Table 3 Agreement calculated with Cohen’s kappa between intensity categories based on EPG and frequency matched categories for PCR DNA copy numbers

From: Comparison of real-time PCR and the Kato-Katz method for the diagnosis of soil-transmitted helminthiasis and assessment of cure in a randomized controlled trial

 

Kappa

P value

Agreement

Weighted Kappa

Trichuris trichiura

 Baseline

0.33

 < 0.001

71.6%

0.35

 Follow-up

0.61

 < 0.001

79.4%

0.63

Hookworm

 Baseline

0.50

 < 0.001

75.3%

0.50

 Follow-up

0.47

 < 0.001

85.0%

0.47

Ascaris lumbricoides

 Baseline

0.45

 < 0.001

63.8%

0.57

 Follow-up

0.74

 < 0.001

98.8%

0.74

  1. Intensity classes of infection calculated in eggs per gram (EPG) for: T. trichiura light (1–999); moderate 1,000–9,999, and heavy ≥ 10,000; for hookworm: light (1–1,999), moderate (2,000–3,999), and heavy (≥ 4,000); for A. lumbricoides light (1–4,999), moderate (5,000–49,999), and heavy infection ≥ 50,000