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Fig. 1 | BMC Microbiology

Fig. 1

From: Oral Lactobacillus strains reduce cytotoxicity and cytokine release from peripheral blood mononuclear cells exposed to Aggregatibacter actinomycetemcomitans subtypes in vitro

Fig. 1

The cytotoxicity (a and c) and IL-1β secretion (b and d) of the PBMCs exposed to the supernatant and CWEs of lactobacilli and A. actinomycetemcomtians, respectively. #Statistically significant lower cytotoxicity (p < 0.001) or IL-1β secretion (p < 0.042) of lactobacilli compared to A. actinomycetemcomtians, Statistically significant higher cytotoxicity of A. actinomycetemcomtians strain NS1, NS2, JP2-like, and OMG3952 (p < 0.001) and IL-1β secretion of A. actinomycetemcomtians strain OMG3952 compared to other strains (p < 0.001), ‡ Statistically significant higher IL-1β secretion of A. actinomycetemcomtians strain NS1, NS2 and JP2-like, except OMG3952, compared to other strains (p < 0.045). The statistical method was Mann Whitney U test and the median of the group is shown as a horizontal line

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