Table 1 MBEC values of vancomycin for S. aureus found in a few studies. Please note ATCC 29213 were tested in several studies with different MBEC values
S. aureus strains | MIC (mg L− 1) | Challenge medium | Biofilm age (h) | Treatment duration (hours) | Biofilm model | MBEC (mg L− 1) |
|---|---|---|---|---|---|---|
ATCC 49230 | 2 | TSB | 24 | 24, 72, 120 | 96-well microtiter plate | > 8000, > 8000, 2000 [9] |
ATCC BAA1556 | 2 | TSB | 24 | 24, 72, 120 | 96-well microtiter plate | > 8000, 8000, 2000 [9] |
ATCC 6538P, MRSA 16 | 0.5, 1 | Not mentioned | 24 | 24 | Beads | > 2000 [10] |
ATCC 29213, UOC18 | 1–2 | CaMHB | 24 | 1–72 | CBD | > 1024 [11] |
ATCC 29213 | 1 | CaMHB | 24 | overnight | CBD | > 1024 [12] |
ATCC 29213 | 1 | MHB | 48 | 24 | CBD | > 512 [13] |
ATCC 35556 | 1 | CaMHB | 24 | 24 | CBD | > 256 [14] |
ATCC 29213, ATCC 33591, VRS5 | 1–2 | CaMHB | 24 | 24 | CBD | > 128 [15] |
B341002, B346846 | 0.5–1 | CaMHB | 24 | overnight | CBD | 128, 64 [16] |
Clinical isolates | 0.5–1 | CaMHB | 18 | 24 | 96-well microtiter plate | 8–16 [17] |
Clinical isolates | 0.5–1 | CaMHB | 18 | 24 | 96-well microtiter plate | 4–32 [18] |
40 MRSA isolates | 1 | TSB | 24 | overnight | CBD | 1–64 [19] |