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Fig. 5 | BMC Microbiology

Fig. 5

From: Enterohaemorrhagic Escherichia coli activates nitrate respiration to benefit from the inflammatory response for initiation of microcolony-formation

Fig. 5

Schematic representation of nitrate-enhancing microcolony-formation of EHEC. Under hypoxic conditions in the intestine, most EHECs possess an immature form of T3SS (T3S machinery). Once epithelial cells are stimulated by interacting with T3SS-positive EHECs, cells produce nitric oxide as a part of the inflammatory response. An increase in the concentration of nitrate derived from nitric oxide enhances the maturation of T3SS in EHEC. Consequently, the efficiency of colony formation on epithelial cells is accelerated

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