Significant association between genes encoding virulence factors with antibiotic resistance and phylogenetic groups in community acquired uropathogenic Escherichia coli isolates

Table 4 Binary logistic regression analysis of virulence-associated genes as predictor of resistance to various antibiotic agents

	Resistance to antibiotic agents
	Azithromycin		Amoxicillin		Imipenem		Gentamycin		Ciprofloxacin		Cefotaxime		Fosfomycin		Cephalexin		Ceftazidime		Ceftriaxone		Nitrofurantoin		Cotrimoxazole
	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p	OR	p
ompA	4.919	0.010	3.386	0.151	0.000	0.999	0.493	0.201	2.012	0.253	2.010	0.197	0.872	1.000	6.493	0.002	2.791	0.092	1.612	0.392	2.406	1.000	0.816	0.745
fimC	0.313	0.753	1.504	0.498	0.000	0.995	1.726	0.080	0.563	0.039	0.482	0.008	0.233	1.000	0.377	0.003	0.616	0.074	0.457	0.005	0.342	0.045	0.648	0.136
irp2	1.618	0.850	0.000	0.995	0.000	0.995	0.672	0.240	1.348	0.363	1.052	0.862	0.456	1.000	0.724	0.360	0.839	0.559	1.254	0.455	1.111	0.857	0.876	0.668
malX	0.939	0.855	1.842	0.457	0.000	0.999	4.700	0.000	5.170	0.000	1.609	0.118	0.000	0.994	0.878	0.736	2.235	0.011	2.058	0.017	3.121	0.996	0.764	0.425
papC	0.301	0.673	26.00	0.000	2.344	1.000	1.427	0.483	0.189	0.000	0.756	0.486	0.027	1.000	1.496	0.344	0.610	0.204	0.970	0.942	0.000	0.995	1.164	0.732
Sfa	0.514	0.041	0.115	0.001	0.79	1.000	0.151	0.001	0.697	0.287	0.584	0.115	3.208	0.993	0.752	0.478	0.523	0.053	0.600	0.137	0.000	0.997	0.578	0.094
hlyA	1.887	0.033	1.711	0.482	1.167	0.994	1.643	0.140	2.651	0.002	1.348	0.370	2.166	1.000	3.433	0.003	1.246	0.478	1.493	0.221	0.000	0.996	0.875	0.676

OR odds ratio, p p-value; Bold p: Significant association (p ≤ 0.05) was shown by binary logistic regression analysis; When p ≤ 0.05, then OR > 1 means that virulence associated gene is introduced as predictor of resistance to antibiotic agent, but OR < 1 means that virulence associated gene is a predictor of susceptibility to antibiotic agent

ISSN: 1471-2180