TY - JOUR AU - Xisto, Mariana Ingrid Dutra da Silva AU - Santos, Suelen S. AU - Rossato, Luana AU - Yoshikawa, Fábio Seiti Yamada AU - Haido, Rosa Maria Tavares AU - de Almeida, Sandro Rogério AU - Barreto-Bergter, Eliana PY - 2020 DA - 2020/08/06 TI - Peptidorhamnomannan from Lomentospora prolificans modulates the inflammatory response in macrophages infected with Candida albicans JO - BMC Microbiology SP - 245 VL - 20 IS - 1 AB - Peptidorhamnomannan is a glycoconjugate that consists of a peptide chain substituted by O- and N-linked glycans, present on the cell surface of Lomentospora prolificans, a saprophytic fungus which is widely distributed in regions with temperate climates. O-linked oligosaccharides from peptidorhamnomannan isolated from Lomentospora prolificans conidia are recognized by macrophages mediating macrophage - conidia interaction. In this work, peptidorhamnomannan was isolated from L. prolificans mycelium cell wall and its role in macrophage - Candida albicans interaction was evaluated. SN - 1471-2180 UR - https://doi.org/10.1186/s12866-020-01931-3 DO - 10.1186/s12866-020-01931-3 ID - Xisto2020 ER -