Fig. 7

Transmission electron microscopy images of Staphylococcus epidermidis in the presence or absence of pseudonajide. S. epidermidis cells were cultured with or without 25 μM of the peptide and imaged at three different time points. Cells were detached from the well plate using disposable tips, and all content was treated following the TEM protocol (Materials and Methods). Dark arrows indicate cell wall defects and membrane disruption in the presence of pseudonajide. Scale bars, 200 nm