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Table 3 MIC against different plant pathogens and hemolysis percentage displayed by the peptide conjugates derived from BP100 tested in this study

From: Screening and identification of BP100 peptide conjugates active against Xylella fastidiosa using a viability-qPCR method

Peptide type Code MIC (μM) Hemolysisd (%)
Xava Psab Eac 50 μM 150 μM 250 μM
Reference peptides tag54 >  100 >  100 >  100 0 0 1
BP100 10–20 7.5–10 7.5–10 1 8 18
BP100 (dimer) BP192 7.5–10 7.5–10 7.5–10 51 69 69
BP198 10–20 10–20 10–20 59 72 72
BP213 1.25–2.5 2.5–5.0 2.5–5.0 90 92 98
BP100 - Melittin [10,11,12,13,14,15,16,17,18,19] BP170 1.25–2.5 2.5–5.0 2.5–5.0 82 93 98
BP171 2.5–5.0 1.25–2.5 2.5–5.0 5 16 34
BP100 - Magainin [4,5,6,7,8,9,10] BP180 2.5–5.0 2.5–5.0 2.5–5.0 12 54 58
BP181 2.5–5.0 1.25–2.5 2.5–5.0 0 0 0
BP100 - Magainin [1,2,3,4,5,6,7,8,9,10] BP175 1.25–2.5 2.5–5.0 5.0–7.5 6 14 32
BP176 2.5–5.0 2.5–5.0 5.0–7.5 3 44 59
BP178 2.5–5.0 2.5–5.0 2.5–5.0 0 3 25
BP100 - Cecropin A [25,26,27,28,29,30,31,32,33,34,35,36,37] BP188 2.5–5.0 1.25–2.5 2.5–5.0 10 24 42
  1. aXav, Xanthomonas axonopodis pv. vesicatoria; bPsa, Pseudomonas syringae pv. syringae; cEa, Erwinia amylovora; dPercent hemolysis plus confidence interval (α = 0.05)