EDTA-modified carbapenem inactivation method (eCIM) for detecting IMP Metallo-β-lactamase–producing Pseudomonas aeruginosa: an assessment of increasing EDTA concentrations

Table 1 Sensitivity and Specificity of eCIM at Respective EDTA Concentrations

	IMP-harboring P. aeruginosa Only	All Evaluable Isolates^a
eCIM Concentration	Sensitivity [n = 26] (95% CI)	Sensitivity [n = 39] (95% CI)	Specificity [n = 8] (95% CI)
5 mM EDTA	0% (0–15%)	33% (19–50%)	100% (63–100%)
10 mM EDTA	35% (17–56%)	56% (40–72%)	100% (63–100%)
20 mM EDTA	85% (65–96%)	90% (76–97%)	100% (63–100%)
40 mM EDTA	100% (87–100%)	100% (91–100%)	100% (63–100%)

^a All evaluable isolates consist of P. aeruginosa harboring IMP, NDM, VIM, and KPC, as well as Enterobacterales harboring IMP and NDM. WT was not included in eCIM sensitivity or specificity analysis

ISSN: 1471-2180