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Fig. 6 | BMC Microbiology

Fig. 6

From: Total RNA and genomic DNA of Lactobacillus gasseri OLL2809 induce interleukin-12 production in the mouse macrophage cell line J774.1 via toll-like receptors 7 and 9

Fig. 6

Relationship between phagocytosis index and IL-12-inducing abilities of various Lactobacilli strains. J774.1 cells were cultivated in the presence of FITC-labelled L. gasseri OLL2809, L. gasseri JCM 1131T, L. plantarum JCM 1149T, and L. crispatus JCM 1185T, respectively. After incubation for 48 h, J774.1 cells were labelled with APC conjugated anti-F4/80 antibody and phagocytosis index was analysed by flow cytometry (a). The concentration of IL-12 in the culture supernatant was quantified by ELISA (b). The IL-12 levels and phagocytosis index of each strain are plotted. Pearson correlation coefficient; r = 0.0666, n = 4, p < 0.05 (c). Data are expressed as mean with SD (n = 3). Difference between multiple groups was analysed by Tukey-Kramer multiple comparison test (a,b). a-d: different letters denote significant differences between the groups (p < 0.05)

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