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Fig. 2 | BMC Microbiology

Fig. 2

From: Optical microscopy reveals the dynamic nature of B. pseudomallei morphology during β-lactam antimicrobial susceptibility testing

Fig. 2

Cell morphology of B. pseudomallei strains cultured in the presence and absence of AMC (a) or CAZ (b). Optical screen images were captured after 6 h. Growth kinetic graphs (black lines) represent the average growth value of triplicate samples (y-axis) over time (18 h, x-axis) and morphology dynamics are described below each image. Strains are designated as resistant (R), intermediate resistant (I), or susceptible (S) to each antibiotic. Indication that a small proportion of spheroplasts were observed (*). Drug concentrations (μg/ml) tested were below, equal to, and above MICs (blue squares) for each strain. CLSI breakpoint for susceptibility (dotted green square), amoxicillin-clavulanic acid (AMC), and ceftazidime (CAZ)

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