Table 1 Demographic and clinical data of IBS-D patients and HCs

Age, Mean (SD)

41.76 (11.57)

38.30 (13.13)

0.139

 Female

24

21

0.219

 Male

46

25

BMI, Mean (SD)

23.36 (3.49)

23.63 (3.76)

0.700

Bristol scale, Mean (SD)

5.26 (0.70)

3.89 (0.74)

0.000

IBS-SSS, Mean (SD)

286.29 (43.14)

120.22 (44.04)

0.000

Duration, Mean (SD), years

3.97 (5.04)

N^f

N

SDS^a

49.89 (9.59)

N

N

SAS^b

48.81 (9.79)

N

N

HADS^c

16.57 (6.58)

N

N

HAM-D^d

13.23 (5.15)

N

N

HAM-A^e

14.53 (5.86)

N

N