From: Effect of deletion of gene cluster involved in synthesis of Enterobacterial common antigen on virulence and immunogenicity of live attenuated Salmonella vaccine when delivering heterologous Streptococcus pneumoniae antigen PspA
Vaccine
PspA expressiona
Total mice/group
Survival/totalb
Percent protectionb
χ12358 (pYA4088)
+
12
4/12
33%
χ9241 (pYA4088)
χ9241 (pYA3493)
–
0/12
0%