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Fig. 4 | BMC Microbiology

Fig. 4

From: Effect of deletion of gene cluster involved in synthesis of Enterobacterial common antigen on virulence and immunogenicity of live attenuated Salmonella vaccine when delivering heterologous Streptococcus pneumoniae antigen PspA

Fig. 4

Serum responses and cross-reactivity. Total serum IgG specific for PspA (a), IgG1 specific for PspA (b) and IgG2a specific for PspA (c) in mice immunized with χ9241 (pYA4088) or χ12358 (pYA4088) were measured according to standard antibodies by ELISA. The error bars represented variations between triplicate wells. Mice were boosted at week 4. ***, P < 0.01 compared to the concentration from the mice immunized with χ9241 (pYA3493). ##, P < 0.01; ###, P < 0.001 compared to the concentration from the mice immunized with χ9241 (pYA4088)

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