Vital members in the gut microbiotas altered by two probiotic Bifidobacterium strains against liver damage in rats

Table 1 The comparisons of liver function variables in the three clustered cohorts in LI09, LI10 and PC groups

Variable	Cluster_1	Cluster_2	Cluster_3
ALB (g/L)	36 ± 1 ^a	39 ± 1 ^a	35 ± 2 ^a
ALT (U/L)	5628 ± 610 ^a	80.0 ± 1.0 ^b	10,393 ± 876 ^c
AST (U/L)	7670 ± 854 ^a	230 ± 25 ^b	12,367 ± 932 ^c
TBA (μmol/L)	351 ± 27 ^a	63 ± 17 ^b	448 ± 26 ^a
TB (μmol/L)	33 ± 13 ^a	2 ± 0.4 ^b	53 ± 30 ^a
GGT (U/L)	17 ± 2 ^a	0.5 ± 0.3 ^b	21 ± 4 ^a
GPDA (U/L)	331 ± 26 ^a	66 ± 4 ^b	427 ± 24 ^a

Note: Cluster_1 to 3 represented the three clusters of cohorts in LI09, LI10 and PC groups identified by partitioning around medoids clustering algorithm based on their intestinal bacterial compositions (see Fig. 4), e.g., Cluster_1 - a mix of rats from all the three groups, Cluster_2 - a mix of rats from LI09 and LI10 groups, Cluster_3 - a mix of remaining rats from LI10 and PC groups. Results were represented in Mean ± S.E., and the groups with different alphabets represented significant difference between the clustered cohorts determined by t-tests

ISSN: 1471-2180