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Table 2 Combination interaction of phenolic compounds with commercial antibiotics against Salmonella enterica serovar Typhimurium (ATCC14028)

From: In vitro synergistic potentials of novel antibacterial combination therapies against Salmonella enterica serovar Typhimurium

Drug CombinationsFIC Index (X)
Galic acid + Ampicillin0.625 (A)
Galic acid + Amoxicillin1.004 (I)
Galic acid + Ceftiofur0.563 (A)
Galic acid + Penicillin G1.016 (I)
Galic acid + Cefotaxime1.004 (I)
Galic acid + Erythromycin1.001 (I)
Galic acid + Thiamphenicol0.625 (A)
Galic acid + Marbofloxacin1.002 (I)
Hamamelitannin + Ampicillin1.002 (I)
Hamamelitannin + Amoxicillin1.001 (I)
Hamamelitannin + Ceftiofur0.625 (A)
Hamamelitannin + Penicillin G1.004 (I)
Hamamelitannin + Cefotaxime0.563 (A)
Hamamelitannin + Erythromycin1.001 (I)
Hamamelitannin + Thiamphenicol1.002 (I)
Hamamelitannin + Marbofloxacin0.563 (A)
Epicatechin + Ampicillin0.750 (A)
Epicatechin + Amoxicillin1.001 (I)
Epicatechin + Ceftiofur0.625 (A)
Epicatechin + Penicillin G1.004 (I)
Epicatechin + Cefotaxime0.750 (A)
Epicatechin + Erythromycin1.016 (I)
Epicatechin + Thiamphenicol1.016 (I)
Epicatechin + Marbofloxacin1.004 (I)
Epicatechin gallate + Ampicillin0.563 (A)
Epicatechin gallate + Amoxicillin1.002 (I)
Epicatechin gallate + Ceftiofur1.001 (I)
Epicatechin gallate + Penicillin G0.502 (A)
Epicatechin gallate + Cefotaxime1.004 (I)
Epicatechin gallate + Erythromycin0.500 (S)
Epicatechin gallate + Thiamphenicol0.504 (A)
Epicatechin gallate + Marbofloxacin1.008 (I)
Epigallocatechin + Ampicillin1.001 (I)
Epigallocatechin + Amoxicillin1.004 (I)
Epigallocatechin + Ceftiofur0.625 (A)
Epigallocatechin + Penicillin G1.008 (I)
Epigallocatechin + Cefotaxime0.502 (A)
Epigallocatechin + Erythromycin0.516 (A)
Epigallocatechin + Thiamphenicol1.004 (I)
Epigallocatechin + Marbofloxacin0.502 (A)
  1. FIC, fractional inhibitory concentration; Synergy, X ≤ 0.5; Additive, 0.5 < X ≤ 1; Indifferent, 1 < X ≤ 2; Antagonist, X > 2; (A), (I) and (S) stand for Additive, Indifferent and Synergy, respectively