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Table 2 Combination interaction of phenolic compounds with commercial antibiotics against Salmonella enterica serovar Typhimurium (ATCC14028)

From: In vitro synergistic potentials of novel antibacterial combination therapies against Salmonella enterica serovar Typhimurium

Drug Combinations FIC Index (X)
Galic acid + Ampicillin 0.625 (A)
Galic acid + Amoxicillin 1.004 (I)
Galic acid + Ceftiofur 0.563 (A)
Galic acid + Penicillin G 1.016 (I)
Galic acid + Cefotaxime 1.004 (I)
Galic acid + Erythromycin 1.001 (I)
Galic acid + Thiamphenicol 0.625 (A)
Galic acid + Marbofloxacin 1.002 (I)
Hamamelitannin + Ampicillin 1.002 (I)
Hamamelitannin + Amoxicillin 1.001 (I)
Hamamelitannin + Ceftiofur 0.625 (A)
Hamamelitannin + Penicillin G 1.004 (I)
Hamamelitannin + Cefotaxime 0.563 (A)
Hamamelitannin + Erythromycin 1.001 (I)
Hamamelitannin + Thiamphenicol 1.002 (I)
Hamamelitannin + Marbofloxacin 0.563 (A)
Epicatechin + Ampicillin 0.750 (A)
Epicatechin + Amoxicillin 1.001 (I)
Epicatechin + Ceftiofur 0.625 (A)
Epicatechin + Penicillin G 1.004 (I)
Epicatechin + Cefotaxime 0.750 (A)
Epicatechin + Erythromycin 1.016 (I)
Epicatechin + Thiamphenicol 1.016 (I)
Epicatechin + Marbofloxacin 1.004 (I)
Epicatechin gallate + Ampicillin 0.563 (A)
Epicatechin gallate + Amoxicillin 1.002 (I)
Epicatechin gallate + Ceftiofur 1.001 (I)
Epicatechin gallate + Penicillin G 0.502 (A)
Epicatechin gallate + Cefotaxime 1.004 (I)
Epicatechin gallate + Erythromycin 0.500 (S)
Epicatechin gallate + Thiamphenicol 0.504 (A)
Epicatechin gallate + Marbofloxacin 1.008 (I)
Epigallocatechin + Ampicillin 1.001 (I)
Epigallocatechin + Amoxicillin 1.004 (I)
Epigallocatechin + Ceftiofur 0.625 (A)
Epigallocatechin + Penicillin G 1.008 (I)
Epigallocatechin + Cefotaxime 0.502 (A)
Epigallocatechin + Erythromycin 0.516 (A)
Epigallocatechin + Thiamphenicol 1.004 (I)
Epigallocatechin + Marbofloxacin 0.502 (A)
  1. FIC, fractional inhibitory concentration; Synergy, X ≤ 0.5; Additive, 0.5 < X ≤ 1; Indifferent, 1 < X ≤ 2; Antagonist, X > 2; (A), (I) and (S) stand for Additive, Indifferent and Synergy, respectively