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Fig. 5 | BMC Microbiology

Fig. 5

From: Bifidobacterium mongoliense genome seems particularly adapted to milk oligosaccharide digestion leading to production of antivirulent metabolites

Fig. 5

Effects of tested CFSM on S. Typhimurium virulence expression. Virulence modulations observed with CFSM obtained from MRS2 (a), MRS2-G (b), MRS2-Wh (c) and MRS2–3′SL (d) media fermented by B. mongoliense after 4 h of incubation. Gene expression ratios of S. Typhimurium were normalised to the housekeeping gene gmk and compared with those of the unfermented media. Values are expressed as the average of at least 3 independent replicates, bars representing standard errors. Negative values (lower than − 2) represent down-regulation of genes and positive values (higher than 2) represent up-regulation of genes. The ratio presented in this figure were considered with a calibrator ratio resulting from a control population (without modulation of gene expression). To determine a significant modulation of the ratio before and after contact with CFSM, a Wilcoxon test for paired samples was performed where p < 0.05 was considered as significant. *P < 0.05

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BMC Microbiology

ISSN: 1471-2180

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