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Table 1 MICs of first-line TB drugs in M. smegmatis transformants

From: LipF increases rifampicin and streptomycin sensitivity in a Mycobacterium tuberculosis surrogate

DrugMinimum inhibitory concentration (MIC)
M. smegmatis pMV261M. smegmatis pMV261-LipF
Rifampicin3.12 μg/mL1.6 μg/mL
Isoniazid32.0 μg/mL32.0 μg/mL
Ethambutol0.5 μg/mL0.5 μg/mL
Pyrazinamide>  200 μg/mL>  200 μg/mL
Streptomycin0.25 μg/mL0.06 μg/mL