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Table 2 Effect of drugs or drug combinations on survival of stationary phase B. henselaea

From: Effect of different drugs and drug combinations on killing stationary phase and biofilms recovered cells of Bartonella henselae in vitro

Drugs (5 μg/ml)CFU per mL after drug exposure
Drug free control2.8 ± 0.4 × 1010
Amikacin8.0 ± 0.2 × 104
Azithromycin6.5 ± 0.4 × 105
Cefuroxime2.2 ± 0.2 × 105
Ciprofloxacin6.0 ± 0.1 × 102
Clofazimine1.6 ± 0.2 × 1010
Daptomycin5.0 ± 0.2 × 107
Disulfiram1.0 ± 0.2 × 107
Doxycycline8.0 ± 0.3 × 106
Gentamicin5.0 ± 0.2 × 102
Methylene blue3.2 ± 0.4 × 104
Miconazole1.5 ± 0.1 × 1010
Nitrofurantoin2.8 ± 0.1 × 102
Rifampin6.0 ± 0.3 × 105
SXT3.5 ± 0.2 × 106
Azithromycin+Amikacin4.3 ± 0.3 × 105
Azithromycin+Rifampin2.0 ± 0.2 × 105
Azithromycin+Cefuroxime5.2 ± 0.2 × 105
Azithromycin+Ciprofloxacin0
Azithromycin+Clofazimine2.2 ± 0.3 × 106
Azithromycin+Daptomycin1.8 ± 0.1 × 105
Azithromycin+Disulfiram1.4 ± 0.2 × 105
Azithromycin+Doxycycline1.2 ± 0.3 × 106
Azithromycin+Gentamicin5.1 ± 0.3 × 104
Azithromycin+Methylene blue0
Azithromycin+Miconazole1.3 ± 0.2 × 105
Azithromycin+Nitrofurantoin4.0 ± 0.3 × 105
Azithromycin+SXT8.5 ± 0.1 × 106
Rifampin+ Amikacin1.6 ± 0.1 × 105
Rifampin+Cefuroxime2.2 ± 0.1 × 104
Rifampin+Ciprofloxacin0
Rifampin+Clofazimine2.8 ± 0.1 × 105
Rifampin+Daptomycin1.2 ± 0.1 × 106
Rifampin+Disulfiram8.5 ± 0.2 × 105
Rifampin+Doxycycline1.2 ± 0.1 × 106
Rifampin+Gentamicin1.6 ± 0.1 × 104
Rifampin+Methylene blue0
Rifampin+ Miconazole8.0 ± 0.3 × 105
Rifampin+Nitrofurantoin1.2 ± 0.1 × 105
Rifampin+SXT1.6 ± 0.1 × 105
  1. aStationary phase B. henselae (6-day old) cells were treated with 5 μg/ml drugs alone or drug combinations for 24 h when the survival of the bacteria was determined by CFU count after wash (see Methods for more details)