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Table 5 Regression statistics and analysis of variance (ANOVA) for Box-Behnken design results

From: Identification of cholesterol-assimilating actinomycetes strain and application of statistical modeling approaches for improvement of cholesterol oxidase production by Streptomyces anulatus strain NEAE-94

Source df Coefficient estimate F-value P-value Prob > F
Model 9 26.55 113.82 <  0.0001*
X1 1 0.04 0.02 0.9071
X2 1 3.18 119.05 0.0001*
X3 1 0.35 1.48 0.2782
X1 X2 1 1.15 7.80 0.0383*
X1 X3 1 −3.25 62.24 0.0005*
X2 X3 1 1.15 7.80 0.0383*
X12 1 −7.69 321.59 <  0.0001*
X22 1 −3.82 79.45 0.0003*
X32 1 −9.84 526.73 <  0.0001*
R2 0.9951 Std. Dev. 0.82  
Adj R2 0.9864 Mean 15.16  
Pred R2 0.9427 C.V. % 5.44  
Adeq Precision 31.469 PRESS 40.03  
  1. * Significant values, “df: Degree of freedom, F: Fishers’s function, P: Level of significance, C.V: Coefficient of variation”