Fig. 4

Diagram showing the conserved genes within the AS-48 subfamily. Arrows show putative genes within the gene cluster. Red shows the bacteriocin structural gene. Orange shows putative membrane proteins/stage II sporulation protein M. Yellow shows putative immunity genes such as-48D1. Green shows putative ABC-transporter proteins such as as-48D and as-48G. Blue shows HlyD/efflux RND transporters such as as-48F. Dark blue shows other transmembrane proteins. Pink shows putative binding-protein-dependent proteins and extracellular solute-binding proteins. Purple shows ABC-II/FtsX permeases such as-48H, based on work done with AS-48 [53]. Grey shows genes of unknown function which may or may not be related to circular bacteriocin production. Figure produced in Easyfig and Inkscape