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Table 1 Innate immune response GO terms significantly enriched in common pathogenic S. maltophilia response (CPSR) genes

From: Identification and characterization of differentially expressed genes in Caenorhabditis elegans in response to pathogenic and nonpathogenic Stenotrophomonas maltophilia

GO category

Term

Count

%

FDR

Biological process

response to stimulus

60

43.48

4.19E-11

 response to stress

55

39.86

3.47E-31

  defense response

52

37.68

2.33E-46

   innate immune response

50

36.23

1.48E-51

   defense response to bacterium

16

11.59

6.58E-12

    defense response to Gram-negative bacterium

14

10.14

4.19E-11

Molecular function

carbohydrate binding

12

8.70

1.84E-04

Cellular component

membrane raft

17

12.32

8.13E-20

  1. Gene ontology (GO) enrichment analysis was performed on the CPSR genes using DAVID Bioinformatics Resources 6.8. Of the 145 CPSR genes, 138 were identified in DAVID and considered for analysis. GO analysis identifies terms relating to the biological process, molecular function, or cellular component that are significantly enriched among a list of genes. Indented terms indicate child terms, or subcategories, of the term listed above, with the parent term left-aligned. Note that the degree of indention of each term does not reflect absolute GO term level within each category. Count is the number of genes corresponding to each GO term. Percent is the count/138 total analyzed. FDR is the false discovery rate-corrected EASE enrichment score to account for multiple testing. Only terms with FDR <0.05 and the most descriptive term for each unique gene list are shown