Skip to main content

Table 1 Significant correlation of differentially abundant microbial taxa and metabolites (n = 15)

From: Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients with colorectal cancer

Microbial taxa

Metabolites

r valuea

p-value

Genus Fusobacterium

(increased in tumour)

4-HB

(decreased in tumour)

0.722

0.002

Genus Prevotella 2

(decreased in tumour)

4-HB

(decreased in tumour)

−0.593

0.020

Family Halomonadaceae

(increased in tumour)

glutamic acid

(increased in tumour)

0.541

0.037

Genus Paeniclostridium

(decreased in tumour)

lactic acid

(increased in tumour)

−0.537

0.039

Genus Enterococcus

(decreased in tumour)

lactic acid

(increased in tumour)

−0.527

0.044

  1. aFor the calculation of the correlations, the signed relative change of microbe abundance and metabolite level between paired tumour and normal tissues were used