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Table 1 Significant correlation of differentially abundant microbial taxa and metabolites (n = 15)

From: Multi-omic profiling reveals associations between the gut mucosal microbiome, the metabolome, and host DNA methylation associated gene expression in patients with colorectal cancer

Microbial taxaMetabolitesr valueap-value
Genus Fusobacterium
(increased in tumour)
4-HB
(decreased in tumour)
0.7220.002
Genus Prevotella 2
(decreased in tumour)
4-HB
(decreased in tumour)
−0.5930.020
Family Halomonadaceae
(increased in tumour)
glutamic acid
(increased in tumour)
0.5410.037
Genus Paeniclostridium
(decreased in tumour)
lactic acid
(increased in tumour)
−0.5370.039
Genus Enterococcus
(decreased in tumour)
lactic acid
(increased in tumour)
−0.5270.044
  1. aFor the calculation of the correlations, the signed relative change of microbe abundance and metabolite level between paired tumour and normal tissues were used